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Tocopherols

Thetocotrienolshave the samemethylstructure at the ring and the sameGreekletter-methyl-notation, but differ from theanalogoustocopherols by the presence of three double bonds in the hydrophobic side chain. Theunsaturationof the tails gives tocotrienols only a singlestereoisomericcarbon (and thus two possibleisomersper structural formula, one of which occurs naturally), whereas tocopherols have three centers. Each form has a differentbiologicalactivity. In overall, the unusual l-isomersof tocotrienols absence almost allvitaminaction, and half of the possible 8 isomers of the tocopherols (those with 2Schiralityat the ring-tail junction) also lack vitamin activity.

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