Abstract
Synthesis and Biological Activity of some Noval Dithiocarbamate Substituted Benzimidazolo-Quinolines
Author(s):Priya M. Madalageri and O. KotreshA series of substituted benzimidazolo-quinoline derivatives bearing a diverse dithiocarbamate moieties were designed and synthesized via a three-component reaction protocol. All these compounds were characterized by means of their IR, 1H NMR and mass spectroscopic data. All the synthesized dithiocarbamate derivatives were screened for antimicrobial activities. Among antibactrial activity, four showed considerable activity of ciprofloxacin and other were found to be moderately active, especially compounds having methoxy and nitro group substitution at 6-position showed a moderate activity. Among fungicidal activity, compounds containing methoxy and methyl substituents at 6- position gave excellent activity and nearly equal to the standard amphotericin B.
