文摘

分光光度法测定辛伐他汀药物剂型

作者(年代):美国Vijaya Saradhi, g . Devala Rao b·西塔拉姆k . Pravallika p Amulya Chowdary和诉信德

一个简单的、敏感的和可再生的spectrophotmetric方法测定了散装辛伐他汀和剂型。This method is based on the formation of colour species on binding of simvastatin with the ligand ferric nitrate and concentrated nitric acid to produce yellowish green colored solution ( max at 390 nm). Results of analysis were validated statistically and by recovery studies. This method is successfully employed for the determination of simvastatin in various pharmaceutical preparations.