文摘

醇和四种分光光度测定

作者(年代):s . Humairaa a . k .家名叫Deya Sanaullahb和美国拉

三个简单的和敏感的光谱光度测量的方法(A、B和C)开发了散装醇和四种定量评估药物和药物剂型。醇和四种方法的基于diazotisation亚硝酸其次是其耦合原位与N -(1 -萘基)乙二胺盐酸盐形式粉红色颜色色原体表现出吸收最大值523.5 nm和比尔定律是服从的浓度范围2 - 10μg /毫升。Method B is also based on the diazotisation of drug with nitrous acid followed by its coupling insitu with -naphthol to form orange coloured chromogen exhibiting absorption maximum at 482.5 nm and Beer’s law is obeyed in the concentration range of 2-10 μg/mL. Method C is based on the reaction of amisulpride with Folin-Ciocalteau (FC) reagent in alkaline condition to form stable blue coloured chromogen with absorption maximum at 736 nm and Beer’s law is obeyed in the concentration range of 10-50 μg/mL. The results are compared with those obtained using UV spectrophotometric method in 0.1N HCl at 226.5 nm