文摘

简单的萃取光度法测定Rupatadine Rupatadine延胡索酸酯从制药配方

作者(年代):r . v .法则、p·d·德赛和s . a . Sawant

简单、敏感、准确的萃取spectroph otometric rupatadine估计的方法已经开发rupatadine延胡索酸酯从制药剂型。方法是基于颜色的形成复合物的药品与试剂(如溴麝香草酚蓝,溴酚蓝和甲基橙在酸性介质。相关的离子复合物形成和定量提取实验con dition氯仿。测量吸光度值在416年,分别为418和422海里。验证了所提出的方法。复苏的方法是由标准的补充方法。The linearity was found to be 1.0 - 12.0
g/mL, 1.0-16.0
g/mL and 1.0-28.0
g/mL for methods I, II and III, respectively. The l ow values of standard deviation and percentage RSD indicate high precision of methods. Hence, these methods are useful for routine estimation of rupatadine as rupa tadine fumarate in tablets.