文摘

关系空腹血糖和糖化血红蛋白在原发性开角青光眼患者眼压

作者(年代):天然橡胶Hazari, A.R.Hazari

目的:原发性开角青光眼(青光眼)是一个失明的主要原因。升高眼内压(IOP)是一个主要的青光眼性视神经病变的危险因素和已被证明是与代谢疾病有关,如糖尿病和高血压。本研究的目的是评估协会的空腹血糖和糖化血红蛋白与眼压青光眼患者,没有糖尿病。材料与方法:- 40例青光眼有或没有糖尿病都包括在内。患者眼压降低治疗和其他眼部疾病被排除在外。对照组由45年龄和性别匹配的个体没有青光眼。空腹血糖和糖化血红蛋白被估计使用商用标准板。结果:发现空腹血糖(FBG)水平显著高于在POAG患者(115.33 + 7.42)和(93.41 + 5.82)糖尿病与控制(90.27 = 11.76)。糖尿病患者的糖化血红蛋白水平显著增加(9.75 + / - -1.64)和非糖尿病(6.8 + / - -0.98)青光眼患者比控制(6.01 + / - -0.94)。意思是眼压明显提高青光眼患者的糖化血红蛋白水平的高度。 FBG (r=+0.51, r=+0.55 respectively) andHbA1c(r=+0.73, r=+0.71 respectively) levels were significantly correlated with IOP in POAG patients with and without diabetes mellitus. Conclusion: - These findings indicate that FBG and HbA1c are associated with increased IOP in POAG patients with and without diabetes mellitus. We conclude that disturbances of glucose metabolism could play a role in glaucoma damage and pathogenesis and monitoring of HbA1c and fasting blood glucose with IOP in glaucoma patient is helpful to be made to assess the magnitude of damage.