摘要

杂草植物(C.Tora)对皮肤真菌病的抗真菌特性

作者(年代):Sarika Jain, Preeti Dubey和Romsha Singh

皮肤真菌病或癣是由人类、宠物和家养动物皮肤真菌感染引起的一种临床疾病。皮肤真菌是一组密切相关的丝状真菌，只感染表皮角质化组织——皮肤、头发和指甲。它们引起多种临床症状，统称为皮肤真菌，通常称为癣或环虫。皮肤植物可分为毛癣菌属、小孢子菌属和表皮菌属。已知所有这些病毒都能在人和动物中引起感染。本研究旨在评价决明子提取物对环虫真菌体外生长的影响。研究了石油醚和甲醇辅助下桂花叶脂类和生物碱类粗提物对环虫或皮肤真菌(主要是毛癣菌和表皮菌)的抑菌活性。在孔扩散法的基础上，给出了脂类和生物碱的提取结果。在本实验中，我们观察到生物碱类化合物比脂类化合物更有效。这些类型的真菌只感染角质化组织，所以蛋白质提取物可能对它们无效。 Five different fungal growth sample collected from two patients (P1 & P2) has shown different size of zone of inhibition in different concentration of alkaloid and lipid compounds (100%, 75%, 50% and 25%). From P1 we got four different fungal colonies (1, 2, 3 and 4) and from P2, only single colony obtained. In the test of alkaloids, in P1, colony 1 did not give any result while colony 2 has shown 9 mm, 7 mm, 6 mm and 4 mm zone of inhibition in 100%, 75%, 50% and 25% conc. respectively. Same like colony 3 and 4 also shown good result, in colony 3 we observed 6 mm, 5 mm and 3-3 mm and in colony 4, 6 mm, 5 mm,5 mm and 3 mm in 100%, 75%, 50% and 25% respectively. But in P-2, colonies did not give any results. In the test of lipid compounds, in P1, colony 1 has shown zone of inhibition of 8 mm on 100% conc. lipid compounds and on 50% and 25% shown 4mm, while 75% give 5 mm. Same like this, colony 2 shown the zone of inhibition of 11 mm, 10 mm, 5 mm on 100%, 75%, 50% and 25%, respectively. And colony 3 & 4 did not give any result. In P2, colony has shown 4 mm and 3 mm in 100% and 75% respectively, but 50% and 25% conc. did not given any results. Effectiveness of the plant extract can be concluded as - Alkaloids > Lipids